Interplay of Genetic and Socioeconomic Predictors of Memory Decline in Older Adults

Using data from the Health and Retirement Study, a nationally representative longitudinal study of persons over age 50, this project uses genetic data and state-of-the art analytic methods to investigate the relationship between genes, early and midlife socioeconomic status, and episodic memory.  Understanding the underlying genetic and gene-environment interactions associated with age-related memory decline may help to reveal the mechanisms of disease, and may also provide targets for potential intervention, treatment, and prevention.