Examined the predictive power of a set of standard psychometric personality and intelligence variables and compared it to the effect of clinical training and practice with respect to wisdom-related performance. A sample of 36 female clinical psychologists and 54 highly educated female control professionals, aged 25-82 yrs, responded verbally to 2 wisdom-related tasks involving life planning and completed a psychometric battery of intelligence and personality measures. Three primary findings were obtained. First, training and practice in clinical psychology was the strongest predictor of wisdom-related performance and, in addition, showed some overlap with personality variables in this predictive relationship. Second, 14% of the variance in wisdom-related performance was accounted for by standard psychometric measures of personality and intelligence. Personality variables were stronger predictors than variables of intelligence. Important personality predictors were Openness to Experience and a middle-range location on the Introversion-Extraversion dimension. Third, wisdom-related performance maintained a sizable degree of measurement independence.